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Table 2 Comparison between review results for nicotine patch in 1994 and 2000

From: Updating a systematic review – what difference did it make? Case study of nicotine replacement therapy

 

Review year

1994

2000

a) All trials

No. of trials

9

30

 

Odds ratio

2.07

1.73

 

95% CI

1.64–2.62

1.56–1.93

 

Χ2 & p for heterogeneity

7.08 (p = 0.53)

41.75(p = 075)

b) Level of support sub group:

No. of trials

4

12

-Low intensity

Odds ratio

2.52

1.74

 

95% CI

1.64–3.87

1.48–2.04

 

Χ2 & p for heterogeneity

4.84(p = 0.18)

18.69(p = 0.096)

-High intensity

No. of trials

5

18

 

Odds ratio

1.99

1.73

 

95% CI

1.49–2.64

1.51–1.99

 

Χ2 & p for heterogeneity

2.55 (p = 0.64)

23.06 (p = 0.15)

c) Length of follow-up subgroups:

No. of trials

3

11

-6 months

Odds ratio

1.96

1.96

 

95% CI

1.44–2.66

1.65–2.34

 

Χ2 & p for heterogeneity

1.74(p = 0.72)

8.06 (p = 0.62)

-12 months

No. of trials

6

19

 

Odds ratio

2.09

1.62

 

95% CI

1.39–3.12

1.42–1.84

 

Χ2 & p for heterogeneity

2.38 (p = 0.67)

30.67 (p = 0.044)