Table 3 Comparison of power for the main treatment effect with power for interaction test, using the population average model (GEE)
From: Testing for heterogeneity among the components of a binary composite outcome in a clinical trial
| Â | OR1 = 0.65 | OR1 = 0.65 | OR1 = 0.70 | OR1 = 0.70 | OR1 = 0.75 | OR1 = 0.75 |
|---|---|---|---|---|---|---|
OR2 | Treatment Effect | Heterogeneity Test | Treatment Effect | Heterogeneity Test | Treatment Effect | Heterogeneity Test |
0.65 | >99.9 | 5.3 | - | - | - | - |
0.70 | 99.9 | 8.1 | 99.4 | 5.0 | - | - |
0.75 | 99.6 | 17.9 | 98.2 | 8.3 | 95.7 | 5.5 |
0.80 | 98.2 | 33.4 | 95.7 | 16.7 | 89.8 | 8.3 |
0.85 | 95.5 | 51.1 | 89.5 | 30.5 | 81.5 | 16.0 |
0.90 | 90.7 | 67.8 | 81.6 | 44.1 | 68.7 | 28.6 |
0.95 | 82.2 | 80.7 | 70.4 | 63.5 | 55.5 | 43.7 |
1.00 | 70.7 | 89.9 | 57.8 | 78.8 | 41.5 | 58.9 |
1.05 | 57.7 | 95.0 | 42.9 | 86.3 | 28.2 | 72.4 |
1.10 | 44.6 | 97.8 | 30.2 | 92.8 | 18.9 | 82.4 |
1.15 | 31.3 | 99.0 | 19.6 | 96.8 | 11.3 | 90.5 |
1.20 | 21.5 | 99.7 | 8.1 | 98.3 | 7.2 | 94.8 |