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Table 3 summary of parameter estimates using both the fixed effect models and the bayesian approach in the anti-malarial trial.

From: Analysis of an ordinal outcome in a multicentric randomized controlled trial: application to a 3- arm anti- malarial drug trial in Cameroon

  

Fixed Approach

 

Bayesian Approach

 

ML

IGLS

GEE

WinBUGS

Category associated cut-points

α 1

3.850

3.880

3.665

3.915

 

(0.63)

(0.64)

(0.63)

(0.50)

α 2

4.237

3.880

4.060

4.359

 

(0.65)

(0.64)

(0.64)

(0.51)

α 3

4.380

4.237

4.203

4.572

 

(0.67)

(0.66)

(0.65)

(0.52)

Treatment (Reference: AQ)

SP/AQ

-1.938*

-1.776*

-1.800 *

-1.760*

 

(0.63)

(0.64)

(0.63)

(0.57)

AQ+SP/AQ

0.537

1.797

2.081

1.601

 

(0.97)

(1.53)

(1.72)

(1.09)

Center (Reference: Yaoundé)

Bertoua/Yaoundé

0.196

0.100

0.242

 
 

(0.51)

(0.55)

(0.55)

 

Gardoua/Yaoundé

0.460

0.458

0.475

 
 

(0.53)

(0.59)

(0.57)

 
  1. *Treatment effect estimates in presence of a center effect. For each outcome category, the SP treatment was less efficacious than the AQ treatment.