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Table 3 Simulation results for the current cumulative incidence estimator and the Markov model estimator of Klein et al.

From: Estimation of current cumulative incidence of leukaemia-free patients and current leukaemia-free survival in chronic myeloid leukaemia in the era of modern pharmacotherapy

 

Sample size 100

Sample size 1,000

 

CCI estimator

Markov model estimator

CCI estimator

Markov model estimator

Time

        
 

MAD* (%)

Coverage of the 95% CI** (%)

MAD* (%)

Coverage of the 95% CI**(%)

MAD* (%)

Coverage of the 95% CI** (%)

MAD* (%)

Coverage of the 95% CI** (%)

1 year

3.7

93.8

3.7

92.8

1.1

95.4

1.1

95.2

2 years

3.2

94.7

3.2

94.4

1.0

94.4

1.0

94.5

3 years

3.1

94.3

3.1

94.2

1.0

95.2

1.0

95.2

4 years

3.2

95.0

3.2

94.3

1.0

95.4

1.0

95.1

5 years

3.6

95.4

3.6

94.7

1.0

93.7

1.0

94.7

6 years

3.6

95.7

3.6

94.5

1.2

92.9

1.2

94.2

7 years

4.2

94.6

4.0

94.0

1.2

95.9

1.2

96.2

8 years

4.8

95.5

4.7

93.4

1.5

94.9

1.4

94.8

9 years

5.7

92.9

5.7

90.4

1.6

95.3

1.6

95.6

10 years

6.4

92.3

6.4

87.3

2.0

94.1

1.9

94.9

  1. * Median absolute deviation between the estimated and true curve.
  2. ** The proportion of 95% point-wise confidence intervals that contained the approximated true curve.