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Table 4 Simulation results for the current leukaemia-free survival estimator and the Markov model estimator of Klein et al.

From: Estimation of current cumulative incidence of leukaemia-free patients and current leukaemia-free survival in chronic myeloid leukaemia in the era of modern pharmacotherapy

  Sample size 100 Sample size 1,000
  CLFS estimator Markov model estimator CLFS estimator Markov model estimator
Time         
  MAD* (%) Coverage of the 95% CI** (%) MAD* (%) Coverage of the 95% CI** (%) MAD* (%) Coverage of the 95% CI** (%) MAD* (%) Coverage of the 95% CI** (%)
1 year 2.3 92.7 2.3 92.7 0.7 93.5 0.7 94.2
2 years 2.7 94.5 2.7 94.3 0.8 94.3 0.9 94.6
3 years 3.0 94.3 3.0 93.2 1.0 95.2 1.0 95.2
4 years 3.4 94.2 3.4 94.1 1.0 94.9 1.0 95.9
5 years 3.5 93.6 3.8 93.3 1.2 93.1 1.2 94.7
6 years 4.1 93.9 4.0 93.2 1.2 95.2 1.3 95.2
7 years 4.2 93.6 4.1 92.5 1.5 95.0 1.4 93.9
8 years 5.0 95.2 4.7 93.2 1.6 94.0 1.5 93.8
9 years 5.8 94.3 5.6 90.1 1.9 93.3 1.8 94.0
10 years 6.7 94.2 6.3 88.1 2.2 95.1 2.1 92.3
  1. * Median absolute deviation between the estimated and true curve.
  2. ** The proportion of 95% point-wise confidence intervals that contained the approximated true curve.