Skip to main content

Advertisement

Table 1 Demographic and clinical characteristics of validation study sample

From: Positive predictive value of automated database records for diabetic ketoacidosis (DKA) in children and youth exposed to antipsychotic drugs or control medications: a tennessee medicaid study

Characteristica All cases Adjudicated
N 30 27
Age, years, median (IQR) 11 (7-14) 11 (8-15)
Gender, no. (%) female 14 (46.7) 13 (48.1)
Race, no. (%)   
   Caucasian 21 (70.0) 19 (70.4)
   African-American 6 (20.0) 6 (22.2)
   Other 3 (10.0) 2 (7.4)
Urban dwelling, no. (%) 19 (63.3) 17 (63.0)
General medical diagnoses, no. (%)   
   Any 15 (50.0) 14 (51.9)
   Cardiovascular 1 (3.3) 1 (3.7)
   Endocrine (non-diabetic, non-DKA) 0 0
   Injury 5 (16.7) 5 (18.5)
   Rheumatologic 2 (6.7) 1 (3.7)
   Pregnancy 1 (3.3) 1 (3.7)
Psychiatric diagnoses, no. (%)   
   Mood disorder 9 (30.0) 8 (29.6)
   Anxiety disorder 3 (10.0) 3 (11.1)
   Attention deficit-hyperactivity disorder 16 (53.3) 15 (55.6)
   Externalizing/impulse control disorders 6 (20.0) 5 (18.5)
   Acute stress/adjustment disorders 5 (16.7) 3 (11.1)
Outpatient visits, median no. (IQR)b 3 (1-10) 3 (1-10)
Medications, psychotropic, no. (%)   
   Antipsychotic drug 6 (20.0) 6 (22.2)
   Antidepressant, SSRI or SNRI 9 (30.0) 9 (33.3)
   Antidepressant, tricyclic 3 (10.0) 3 (11.1)
   Antidepressant, other 1 (3.3) 1 (3.7)
   ADHD (stimulants, atomoxetine) 22 (73.3) 19 (70.4)
   Benzodiazepine 4 (13.3) 4 (14.8)
   Mood stabilizer (VPA, CBMZ, LAM) 2 (6.7) 2 (7.4)
  1. a Corresponds with the value at the beginning of follow-up (t0) in the study cohort, unless otherwise specified.
  2. b Corresponds with the value during the year prior to the beginning of follow-up in the study cohort (e.g., the time interval [t0-365 days, t0]).
  3. Key: ADHD = attention deficit-hyperactivity disorder, CBMZ = carbamazepine, LAM = lamotrigine, SNRI = serotonin-norepinephrine re-uptake inhibitor (venlafaxine, duloxetine), SSRI = selective serotonin re-uptake inhibitor (fluoxetine, paroxetine, sertraline, citalopram, fluvoxamine, escitalopram), VPA = valproic acid.