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Table 2 Positive predictive value (PPV) of computer case definition for diabetic ketoacidosis

From: Positive predictive value of automated database records for diabetic ketoacidosis (DKA) in children and youth exposed to antipsychotic drugs or control medications: a tennessee medicaid study

  PPV (%)a 95% Confidence Intervala
Overall 88.9 71.9 to 96.1
Stratified analyses   
   By psychotropic drug exposureb   
Antipsychotic drug 83.3 43.6 to 97.0
Other psychotropic drugs 90.0 71.1 to 97.3
   By age strata   
Upper (ages 11-24 years) 100.0 81.6 to 100.0
Lower (age ≤ 10 years) 70.0 39.7 to 89.2
   By gender   
Male 100.0 78.5 to 100.0
Female 76.9 49.7 to 91.8
   By ADHD diagnosis   
Yes 80.0 54.8 to 93.0
No 100.0 75.8 to 100.0
  1. a The positive predictive value (PPV) of the DKA case definition was calculated with 95% confidence intervals (CI) for binomial proportions using Wilson's formula.
  2. b The cohort consisted of recent initiators of antipsychotics or control medications (mood stabilizers, ADHD drugs, antidepressants, benzodiazepines) who filled a qualifying prescription for a study drug, had no fill more than 90 days prior to the qualifying prescription, and had at ≥ 365 prior consecutive days with no filled prescription.
  3. c The underlying cohort consisted of children and youth (aged 6-24 years).
  4. Key: ADHD = attention deficit-hyperactivity disorder