| |
PPV (%)a
|
95% Confidence Intervala
|
|---|
|
Overall
|
88.9
|
71.9 to 96.1
|
|
Stratified analyses
| | |
|
By psychotropic drug exposureb
| | |
|
Antipsychotic drug
|
83.3
|
43.6 to 97.0
|
|
Other psychotropic drugs
|
90.0
|
71.1 to 97.3
|
|
By age strata
| | |
|
Upper (ages 11-24 years)
|
100.0
|
81.6 to 100.0
|
|
Lower (age ≤ 10 years)
|
70.0
|
39.7 to 89.2
|
|
By gender
| | |
|
Male
|
100.0
|
78.5 to 100.0
|
|
Female
|
76.9
|
49.7 to 91.8
|
|
By ADHD diagnosis
| | |
|
Yes
|
80.0
|
54.8 to 93.0
|
|
No
|
100.0
|
75.8 to 100.0
|
-
a The positive predictive value (PPV) of the DKA case definition was calculated with 95% confidence intervals (CI) for binomial proportions using Wilson's formula.
-
b The cohort consisted of recent initiators of antipsychotics or control medications (mood stabilizers, ADHD drugs, antidepressants, benzodiazepines) who filled a qualifying prescription for a study drug, had no fill more than 90 days prior to the qualifying prescription, and had at ≥ 365 prior consecutive days with no filled prescription.
-
c The underlying cohort consisted of children and youth (aged 6-24 years).
-
Key: ADHD = attention deficit-hyperactivity disorder
