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Table 2 Distribution of Pair-wise Interventions in meta-analyses in the CDSR

From: Characteristics of meta-analyses and their component studies in the Cochrane Database of Systematic Reviews: a cross-sectional, descriptive analysis

  Second Intervention
First Intervention vs. Control vs. Placebo vs. Pharm Vs. Non-Pharm1 from same category vs. Non-Pharm1 from different category Total
Pharmacological 4027 (18%) 4321 (19%) 5571 (25%) n/a 186 (<1%) 14105 (63%)
Vaccines 95 (<1%) 113 (<1%) 0 (0%) 49 (<1%) 0 (0%) 257 (1%)
Surgical 241 (1%) 2 (<1%) 29 (<1%) 1204 (5%) 86 (<1%) 1562 (7%)
Medical devices 706 (3%) 50 (<1%) 82 (<1%) 941 (4%) 159 (<1%) 1938 (9%)
Cellular and gene 29 (<1%) 6 (<1%) 0 (0%) 57 (<1%) 7 (<1%) 99 (<1%)
Radiotherapy 124 (<1%) 65 (<1%) 3 (<1%) 56 (<1%) 63 (<1%) 311 (1%)
Physical 318 (1%) 10 (<1%) 8 (<1%) 72 (<1%) 39 (<1%) 447 (2%)
Educational 303 (1%) 4 (<1%) 1 (<1%) 34 (<1%) 27 (<1%) 369 (2%)
Behavioural 380 (2%) 7 (<1%) 3 (<1%) 165 (<1%) 14 (<1%) 569 (3%)
Screening 17 (<1%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 17 (<1%)
Complementary 216 (1%) 104 (<1%) 41 (<1%) 8 (<1%) 19 (<1%) 388 (2%)
Psychological 379 (2%) 1 (<1%) 6 (<1%) 116 (<1%) 44 (<1%) 546 (2%)
Resources and infrastructure 506 (2%) 0 (0%) 14 (<1%) 52 (<1%) 33 (<1%) 605 (3%)
Complex 505 (2%) 36 (<1%) 43 (<1%) 200 (<1%) 154 (<1%) 938 (4%)
Other 188 (1%) 44 (<1%) 8 (<1%) 51 (<1%) 11 (<1%) 302 (1%)
Total 8034 (36%) 4763 (21%) 5809 (26%) 3005 (13%) 842 (4%) 22453
  1. 1Non-Pharm = all intervention categories as listed for the First intervention, other than Pharmacological
  2. n/a = not applicable