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Table 1 Catalogue of simulation designs

From: Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study

Design Scenario Number of centres Centre size ICC
Balance 1 45 4  
  2 18 10  
  3 6 30  
Chance imbalance 4 45 4  
  5 18 10 0 - 0.75
  6 6 30  
Blocking
(size = 2)
7 17 1, 1, 4, 5, 5, 5, 8, 8, 10, 10, 10  
Blocking
(size = 4)
8 17 10, 15, 15, 20, 25, 28  
Blocking
(size = 6)
9 46 Same as Table 2 0.125
  1. ICC: Intraclass (intracentre) correlation