Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study

Table 2 Centre composition of the COMPETE II trial

Number of patients per centre	Number of Centres
1	3
2	0
3	1
4	4
5	1
6	1
7	2
8	3
9	4
10	3
11	5
12	3
13	2
14	0
15	3
16	3
17	0
18	2
19	2
20	1
21	0
22	1
23	1
24	0
25	1

ISSN: 1471-2288

Number of patients per centre	Number of Centres
1	3
2	0
3	1
4	4
5	1
6	1
7	2
8	3
9	4
10	3
11	5
12	3
13	2
14	0
15	3
16	3
17	0
18	2
19	2
20	1
21	0
22	1
23	1
24	0
25	1

Number of patients per centre	Number of Centres
1	3
2	0
3	1
4	4
5	1
6	1
7	2
8	3
9	4
10	3
11	5
12	3
13	2
14	0
15	3
16	3
17	0
18	2
19	2
20	1
21	0
22	1
23	1
24	0
25	1

Number of patients per centre	Number of Centres
1	3
2	0
3	1
4	4
5	1
6	1
7	2
8	3
9	4
10	3
11	5
12	3
13	2
14	0
15	3
16	3
17	0
18	2
19	2
20	1
21	0
22	1
23	1
24	0
25	1