|
Scenario Number
|
Treatment effect (HR)
|
% with 'good' Prognosis
|
'Good' prognosis Survival
|
Crossover probabilities ('good' and 'poor' prognosis)
|
Table Number
|
|---|
| |
0.9
|
0.7
|
30%
|
75%
|
×1.2
|
×3
|
10% and 25%
|
50% and 75%
| |
|---|
|
1
|
√
| |
√
| |
√
| |
√
| |
3
|
|
2
| |
√
|
√
| |
√
| |
√
| |
3
|
|
3
|
√
| | |
√
|
√
| |
√
| |
Additional file 1
|
|
4
| |
√
| |
√
|
√
| |
√
| |
Additional file 1
|
|
5
|
√
| |
√
| |
√
| | |
√
|
4
|
|
6
| |
√
|
√
| |
√
| | |
√
|
4
|
|
7
|
√
| | |
√
|
√
| | |
√
|
Additional file 2
|
|
8
| |
√
| |
√
|
√
| | |
√
|
Additional file 2
|
|
9
|
√
| |
√
| | |
√
|
√
| |
5
|
|
10
| |
√
|
√
| | |
√
|
√
| |
5
|
|
11
|
√
| | |
√
| |
√
|
√
| |
Additional file 3
|
|
12
| |
√
| |
√
| |
√
|
√
| |
Additional file 3
|
|
13
|
√
| |
√
| | |
√
| |
√
|
6
|
|
14
| |
√
|
√
| | |
√
| |
√
|
6
|
|
15
|
√
| | |
√
| |
√
| |
√
|
Additional file 4
|
|
16
| |
√
| |
√
| |
√
| |
√
|
Additional file 4
|
