Table 3 Difference in expected survival (in months) between interventions as obtained with random effects network meta-analysis model with and without treatment-by-covariate interaction
| Â | Random effects model without covariate interaction (model 1) | Random effects model with treatment specific covariate interaction (model 2) | Random effects model with constant treatment-by-covariate interaction (model 3) | |||
|---|---|---|---|---|---|---|
| Â | Median of posterior distribution | 95% Credible Interval | Median of posterior distribution | 95% Credible Interval | Median of posterior distribution | 95% Credible Interval |
DTIC + IFN vs. DTIC | −1.12 | (−4.20; 3.49) | −2.46 | (−5.72; 1.91) | −1.90 | (−5.10; 2.22) |
DTIC + non-IFN vs. DTIC | 3.63 | (−1.72; 10.75) | 3.77 | (−1.04; 10.72) | 3.21 | (−2.39; 9.65) |
non-DTIC vs. DTIC | 2.66 | (−2.38; 13.49) | 1.16 | (−7.51; 25.76) | 6.60 | (−0.78; 21.39) |
DTIC + non-IFN vs. DTIC + IFN | 4.71 | (−1.38; 11.37) | 6.26 | (0.26; 13.29) | 5.13 | (−1.15; 11.50) |
non-DTIC vs. DTIC + IFN | 3.81 | (−2.40; 14.11) | 3.46 | (−6.00; 27.88) | 8.48 | (−0.65; 24.00) |
non-DTIC vs. DTIC + non-IFN | −0.84 | (−9.15; 10.3) | −2.79 | (−13.90; 22.17) | 3.27 | (−6.72; 20.74) |