Table 5 LDL tests performed and LDL test results available by lipid lowering treatment in patients initiating lipid-lowering therapy, including patient subgroups with diabetes (DM) or rheumatoid arthritis (RA)
All patients | LDL test performed | LDL test results available | LDL level | HDL level | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Initiated medication | N | % | N | % | N | % of total N | % of ordered | mean | s.d. | mean | s.d. | |
All | Any statin alone | 655,211 | 93 | 395,496 | 60.4 | 165,380 | 25.2 | 41.8 | 145.3 | 38.6 | 50.2 | 14.5 |
Any statin high intensity* | 173,979 | 25 | 98,309 | 56.5 | 41,320 | 23.7 | 42.0 | 144.2 | 45.5 | 49.2 | 14.3 | |
Any statin low intensity | 481,232 | 68 | 297,187 | 61.8 | 124,060 | 25.8 | 41.7 | 145.7 | 36 | 50.6 | 14.6 | |
Simvastatin alone | 282,658 | 40 | 176,697 | 62.5 | 73,193 | 25.9 | 41.4 | 147.0 | 36.3 | 50.2 | 14.4 | |
Simvastatin high dose (>40 mg) | 11,354 | 2 | 5,912 | 52.1 | 2,192 | 19.3 | 37.1 | 135.6 | 49.5 | 48 | 13.6 | |
Simvastatin low dose | 271,304 | 39 | 170,785 | 62.9 | 71,001 | 26.2 | 41.6 | 147.3 | 35.8 | 50.2 | 14.4 | |
Vytorin alone | 24,931 | 4 | 12,966 | 52 | 6,820 | 27.4 | 52.6 | 142.2 | 47.6 | 49.6 | 14.3 | |
Vytorin high dose (>40 mg simvast) | 1,069 | 0 | 563 | 52.7 | 223 | 20.9 | 39.6 | 124.1 | 56.7 | 48.1 | 13.5 | |
Vytorin low dose | 23,862 | 3 | 12,403 | 52 | 6,597 | 27.6 | 53.2 | 142.8 | 47.1 | 49.6 | 14.4 | |
Ezetimibe alone | 20,509 | 3 | 11,412 | 55.6 | 5,334 | 26 | 46.7 | 143.2 | 38.1 | 51.5 | 14.9 | |
Ezetimibe + statin | 2,833 | 0 | 1,834 | 64.7 | 720 | 25.4 | 39.3 | 145.7 | 47.7 | 48.2 | 13.5 | |
Total: | 703,484 | |||||||||||
DM | Any statin alone | 103,664 | 93 | 69,788 | 67.3 | 25,927 | 25 | 37.2 | 124.8 | 37.4 | 46.5 | 13.1 |
Any statin high intensity* | 28,472 | 26 | 18,069 | 63.5 | 6,909 | 24.3 | 38.2 | 122.3 | 43.3 | 45.8 | 13.1 | |
Any statin low intensity | 75,192 | 67 | 51,719 | 68.8 | 19,018 | 25.3 | 36.8 | 125.7 | 35.0 | 46.8 | 13.1 | |
Simvastatin alone | 46,414 | 42 | 32,207 | 69.4 | 11,670 | 25.1 | 36.2 | 126.8 | 35.6 | 46.5 | 13.0 | |
Simvastatin high dose (>40 mg) | 2,498 | 2 | 1,513 | 60.6 | 521 | 20.9 | 34.4 | 117.1 | 46.2 | 45.6 | 12.6 | |
Simvastatin low dose | 43,916 | 39 | 30,694 | 69.9 | 11,149 | 25.4 | 36.3 | 127.2 | 35.0 | 46.6 | 13.0 | |
Vytorin alone | 4,049 | 4 | 2,324 | 57.4 | 1,086 | 26.8 | 46.7 | 122.9 | 44.4 | 45.6 | 13.4 | |
Vytorin high dose (>40 mg simvast) | 269 | 0 | 169 | 62.8 | 58 | 21.6 | 34.3 | 105.6 | 41.6 | 46.3 | 14.0 | |
Vytorin low dose | 3,780 | 3 | 2,155 | 57 | 1,028 | 27.2 | 47.7 | 123.8 | 44.4 | 45.6 | 13.4 | |
Ezetimibe alone | 3,459 | 3 | 2,092 | 60.5 | 884 | 25.6 | 42.3 | 126.9 | 37.7 | 47.0 | 13.1 | |
Ezetimibe + statin | 512 | 1 | 372 | 72.7 | 135 | 26.4 | 36.3 | 133.1 | 44.5 | 44.8 | 11.8 | |
Total: | 111,684 | |||||||||||
RA | Any statin alone | 4,118 | 91 | 2,425 | 58.9 | 833 | 20.2 | 34.4 | 138.5 | 39.4 | 54.7 | 16.5 |
Any statin high intensity* | 1,044 | 23 | 575 | 55.1 | 205 | 19.6 | 35.7 | 135.4 | 50.9 | 53.6 | 17.8 | |
Any statin low intensity | 3,074 | 68 | 1,850 | 60.2 | 628 | 20.4 | 33.9 | 139.5 | 34.8 | 55.1 | 16.0 | |
Simvastatin alone | 1,749 | 39 | 1,070 | 61.2 | 360 | 20.6 | 33.6 | 141.6 | 33.4 | 54.3 | 15.5 | |
Simvastatin high dose (>40 mg) | 70 | 2 | 37 | 52.9 | 14 | 20 | 37.8 | 134.6 | 44.2 | 46.5 | 12.0 | |
Simvastatin low dose | 1,679 | 37 | 1,033 | 61.5 | 346 | 20.6 | 33.5 | 141.9 | 32.9 | 54.6 | 15.6 | |
Vytorin alone | 174 | 4 | 85 | 48.9 | 43 | 24.7 | 50.6 | 142.6 | 45.6 | 52.8 | 16.3 | |
Vytorin high dose (>40 mg simvast) | 9 | 0 | 4 | 44.4 | 2 | 22.2 | 50.0 | 177.0 | 76.4 | 52 | 22.6 | |
Vytorin low dose | 165 | 4 | 81 | 49.1 | 41 | 24.8 | 50.6 | 141.0 | 44.5 | 52.8 | 16.3 | |
Ezetimibe alone | 210 | 5 | 126 | 60 | 55 | 26.2 | 43.7 | 137.5 | 31.3 | 56.8 | 16.7 | |
Ezetimibe + statin | 21 | 1 | 14 | 66.7 | 4 | 19 | 28.6 | 144.0 | 45.5 | 49.0 | 10.4 | |
Total: | 4,523 | |||||||||||