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Table 3 Sex/Gender: Health equity plausibility ratings for each question, across 10 systematic reviews

From: Systematic reviews need to consider applicability to disadvantaged populations: inter-rater agreement for a health equity plausibility algorithm

 

Sex: Proportion judging important differences exist across sex

Systematic review

Question 1: Patient differences

Question 2: Delivery of intervention

Question 3: Comparator

Description in systematic review

INTER-RATER AGREEMENT on Q1 ≥70%

Mass media for HIV testing

96%

70%

57%

Sex differences not analyzed or discussed

Antidepressants for depression in primary care

92%

67%

50%

Sex not discussed or analyzed

Vaccines for MMR in children

8%

17%

25%

Sex not discussed or analyzed.

Primary safety belt laws

83%

67%

33%

Men have higher uptake of seatbelts

Psychological therapy for PTSD

83%

83%

52%

Studies including only females, all of whom had been assaulted, produced more positive results than the overall results.

INTER-RATER AGREEMENT on Q1 <70%

Population tobacco control

70%

48%

48%

No differences found across sex

First line antihypertensives

65%

48%

43%

Females represented 45% of population. No subgroup analyses conducted on sex

Surgery for age-related cataract

67%

67%

67%

Sex not discussed

Hand washing for diarrhoea

67%

50%

50%

Analyses were age and sex adjusted, differences not discussed

ACT for malaria

33%

33%

25%

Sex not discussed

Fleiss Kappa

0.199

0.068

0.005

 
  1. Notes: PTSD: Post-traumatic stress disorder; SES: socioeconomic status; MMR: Measles, mumps and rubella vaccine.