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Table 3 Sex/Gender: Health equity plausibility ratings for each question, across 10 systematic reviews

From: Systematic reviews need to consider applicability to disadvantaged populations: inter-rater agreement for a health equity plausibility algorithm

  Sex: Proportion judging important differences exist across sex
Systematic review Question 1: Patient differences Question 2: Delivery of intervention Question 3: Comparator Description in systematic review
Mass media for HIV testing 96% 70% 57% Sex differences not analyzed or discussed
Antidepressants for depression in primary care 92% 67% 50% Sex not discussed or analyzed
Vaccines for MMR in children 8% 17% 25% Sex not discussed or analyzed.
Primary safety belt laws 83% 67% 33% Men have higher uptake of seatbelts
Psychological therapy for PTSD 83% 83% 52% Studies including only females, all of whom had been assaulted, produced more positive results than the overall results.
Population tobacco control 70% 48% 48% No differences found across sex
First line antihypertensives 65% 48% 43% Females represented 45% of population. No subgroup analyses conducted on sex
Surgery for age-related cataract 67% 67% 67% Sex not discussed
Hand washing for diarrhoea 67% 50% 50% Analyses were age and sex adjusted, differences not discussed
ACT for malaria 33% 33% 25% Sex not discussed
Fleiss Kappa 0.199 0.068 0.005  
  1. Notes: PTSD: Post-traumatic stress disorder; SES: socioeconomic status; MMR: Measles, mumps and rubella vaccine.