From: Search strategies to identify reports on “off-label” drug use in EMBASE
Search query | Cumulative number of relevant records retrieved | Cumulative number of records retrieved | Cumulative sensitivity/full set (%) | Cumulative sensitivity/EMBASE set (%) | Cumulative Precision (%) | |
---|---|---|---|---|---|---|
1 | off label*.af. | 3150 | 3577 | 77.45 | 81.90 | 88.06 |
2 | (unlicensed not (unlicensed aide* or unlicensed assist* or unlicensed car* or (Unlicensed adj2 heal*)or unlicensed home* or (killer adj2 cell*) or (unlicensed adj2 individual*) or (unlicensed adj2 nurs*) or (unlicensed adj4 practi*) or (unlicensed adj2 physician*) or (unlicensed adj2 operat*) or (unlicensed adj2 person*) or unlicensed profession* or unlicensed rid* or (unlicensed adj3 staff*) or unlicensed therapist* or (unlicensed adj5 vaccine*) or unlicensed vendor* or (unlicensed adj2 work*) or (unlicensed adj2 employe*) or device*or dentist*or driver or driving or herbal or medical graduate* or motor* or pesticide*or premis*or prostitute*or restaurant*or veterinary or worker*)).af., | 3272 | 3858 | 80.45 | 85.08 | 84.81 |
3 | (unapprove* adj2 us*).af. | 3331 | 3947 | 81.90 | 86.61 | 84.39 |
4 | (unapprove* adj5 indication*).af. | 3367 | 3986 | 82.79 | 87.55 | 84.47 |
5 | off li?en?e.af. | 3425 | 4053 | 84.21 | 89.05 | 84.51 |
6 | ((no* licen?ed for adj3 use*) not now licen?ed).af. | 3476 | 4136 | 85.47 | 90.38 | 84.04 |
7 | (unapprove* adj2 drug*).af. | 3493 | 4181 | 85.89 | 90.82 | 83.54 |
8 | (outside adj3 licen?e*).af. | 3511 | 4211 | 86.33 | 91.29 | 83.38 |
9 | unlabel* us*.af. | 3538 | 4241 | 86.99 | 91.99 | 83.42 |
10 | labeled indication*.af. | 3549 | 4270 | 87.26 | 92.28 | 83.11 |
11 | nonapprove*.af. | 3569 | 4317 | 87.76 | 92.80 | 82.67 |
12 | registered indication*.af. | 3585 | 4348 | 88.15 | 93.21 | 82.45 |
13 | offlabel*.af. | 3590 | 4353 | 88.27 | 93.34 | 82.47 |
14 | (unlabel* adj3 indication*).af. | 3598 | 4361 | 88.47 | 93.55 | 82.50 |
15 | non fda approve*.af. | 3611 | 4388 | 88.79 | 93.89 | 82.29 |
16 | ((no* licen?ed for adj3 indication*) not now licen?ed).af. | 3624 | 4402 | 89.11 | 94.23 | 82.33 |
17 | (appropriate indication adj3 us*).af. | 3630 | 4413 | 89.25 | 94.38 | 82.26 |
18 | (be???d* adj2 licen?ed indication*).af. | 3633 | 4417 | 89.33 | 94.46 | 82.25 |
19 | (us* without adj2 indication*).af. | 3638 | 4428 | 89.45 | 94.59 | 82.16 |
20 | (prescri* outside adj4 guideline*).af. | 3643 | 4434 | 89.57 | 94.72 | 82.16 |
21 | (inappropriate adj5 indication adj2 us*).af. | 3647 | 4441 | 89.67 | 94.83 | 82.12 |
22 | (non evidence base* us*).af. | 3650 | 4446 | 89.75 | 94.90 | 82.10 |
23 | (or/1-22) not (stent* or veterinar*).af. | 3635 | 4158 | 89.38 | 94.51 | 87.42 |