From: Individual patient data meta-analysis of survival data using Poisson regression models

Framework | Model | Treatment effect | Trial effect | Cox | Poisson (1) | Poisson (0.5) | Poisson (0.25) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|

Hazard ratio | 95% CI | Hazard ratio | 95% CI | Hazard ratio | 95% CI | Hazard ratio | 95% CI | ||||||||

Classical | A | Fixed | Proportional | 0.877 | 0.793 | 0.970 | 0.877 | 0.793 | 0.970 | 0.877 | 0.793 | 0.970 | 0.877 | 0.793 | 0.970 |

B | Fixed | Stratified | 0.880 | 0.795 | 0.973 | 0.879 | 0.795 | 0.973 | 0.880 | 0.796 | 0.973 | 0.880 | 0.796 | 0.973 | |

C | Random | Proportional | - | - | - | 0.877 | 0.793 | 0.970 | 0.877 | 0.793 | 0.970 | 0.877 | 0.793 | 0.970 | |

D | Random | Stratified | - | - | - | 0.879 | 0.795 | 0.973 | 0.880 | 0.796 | 0.973 | 0.880 | 0.796 | 0.973 | |

Bayesian | A | Fixed | Proportional | - | - | - | 0.877 | 0.796 | 0.971 | 0.878 | 0.792 | 0.969 | 0.876 | 0.792 | 0.970 |

B | Fixed | Stratified | - | - | - | 0.880 | 0.796 | 0.971 | 0.879 | 0.793 | 0.975 | 0.879 | 0.794 | 0.971 | |

C | Random | Proportional | - | - | - | 0.874 | 0.756 | 0.994 | 0.871 | 0.747 | 0.994 | 0.873 | 0.748 | 0.998 | |

D | Random | Stratified | - | - | - | 0.876 | 0.755 | 0.996 | 0.876 | 0.755 | 1.002 | 0.873 | 0.760 | 1.000 |