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Table 2 Log-transformed concentrations of CRP and SAA measured by the two analytical assays (nepholometry and ELISA) in COPD patients and healthy controls

From: Determination of inflammatory biomarkers in patients with COPD: a comparison of different assays

 

Entire cohort

(n = 133)

COPD

(n = 88)

Controls

(n = 45)

p value*

logCRP (Ne)

0.5 (0.4)

0.6 (0.4)

0.3 (0.4)

0.002

logCRP (ELISA)

0.2 (0.6)

0.3 (0.5)

0.04 (0.7)

0.026

P value†

< 0.001

< 0.001

0.001

 

logSAA (Ne)

0.7 (0.4)

0.7 (0.4)

0.5 (0.3)

0.022

logSAA (ELISA)

0.7 (0.4)

0.8 (0.4)

0.5 (0.5)

0.003

P value†

NS

NS

NS

 
  1. Data expressed as the mean (standard deviation). *p value calculated by unpaired Student's t test. †p value for the difference between nephelometry and ELISA calculated by paired Student's t test.
  2. logCRP (Ne): log-transformed concentrations of C-reactive protein measured by nephelometry.
  3. logCRP (ELISA): log-transformed concentrations of C-reactive protein measured by ELISA.
  4. logSAA (Ne): log-transformed concentrations of serum amyloid A measured by nephelometry.
  5. logSAA (ELISA): log-transformed concentrations of serum amyloid A measured by ELISA.