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Table 2 Impact of effect size. Based on 1000 simulated datasets with sample size of 500 equally distributed between direct and indirect effects. Impact of effect size on model performance in evaluating the total effect of the repeated independent variable on the repeated outcome.

From: Non-linear mixed models in the analysis of mediated longitudinal data with binary outcomes

Simulated Data SEM Scaled NLMM
Effect Size Bias (%) Coverage (%) Power (%) Bias (%) Coverage (%) Power (%)
Logit Link Results
0.2 -1.1 96 38 -2.0 96 37
0.3 0.2 94 68 -0.6 95 68
0.4 -0.6 96 89 -1.3 95 89
0.5 1.3 95 99 0.4 95 98
Probit Link Results
0.2 7.6 94 47 -0.7 95 58
0.3 8.8 95 79 0.2 94 88
0.4 11.1 93 95 1.7 93 98
0.5 11.7 95 >99 1.6 95 >99