Figure 1From: When is it rational to participate in a clinical trial? A game theory approach incorporating trust, regret and guilt Model of clinical research according to the trust version of the prisoner’s game dilemma. The inset shows the equipoise model; e-success of experimental treatment; s-success of standard treatments. R-regret; G-guilt; U1 to U4: the patient’s utilities related to treatment success or failure; V1-V4: the researcher’s utilities related to treatment success or failure; Exp Rx- experimental treatment; Std Rx- standard treatment NA- not applicable (see text for details).Back to article page