BMC Medical Research Methodology

Table 5 The number of matched-pairs ( N ) needed to reach power of 50%, 60%, 70%, 80%, and 90%, averaged over five values of θ and three values of p ₁₊ , for three values of Δ=p ₊₁ −p ₁₊

From: The McNemar test for binary matched-pairs data: mid-p and asymptotic are better than exact conditional

	Nto reach power of
	50%	60%	70%	80%	90%
Δ=0.15
McNemar asymptotic	56	69	85	103^∗	123^∗
McNemar asymptotic w/CC	68	82	98	114^∗	129^∗
McNemar exact	67	81	96	113^∗	129^∗
McNemar mid-p	57	71	87	104^∗	123^∗
Exact unconditional	57	71	88	106^∗	126^∗
Δ=0.25
McNemar asymptotic	23	28	34	42	54
McNemar asymptotic w/CC	30	35	41	50	63
McNemar exact	29	34	41	49	62
McNemar mid-p	24	29	35	43	56
Exact unconditional	24	29	35	43	56
Δ=0.35
McNemar asymptotic	13	15	18	23	29
McNemar asymptotic w/CC	18	21	24	28	34
McNemar exact	18	21	23	27	34
McNemar mid-p	15	17	20	24	30
Exact unconditional	15	17	20	24	29

^∗Values above 100 estimated by linear extrapolation.
This table should not be used for sample size calculations.

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ISSN: 1471-2288

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