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Table 3 Results from simulations based on MIST2 dataset (OR = 0.23)

From: Accounting for centre-effects in multicentre trials with a binary outcome – when, why, and how?

 

Mean treatment effect

Power (%)

Convergence (%)

Unadjusted for centre-effects

0.20

66.5

97.1

Fixed-effects

0.19

65.0

96.3

Random-effects

0.19

66.0

96.1

GEE

0.20

66.5

98.0

Mantel-Haenszel

0.22

50.3

95.9