BMC Medical Research Methodology

Table 2 Hypothetical Data for an Ordered Marker From a Nested Case-Control Design

From: Markers for early detection of cancer: Statistical guidelines for nested case-control studies

	1	2	3	4	5
No cancer	960	20	10	8	2	1000
Cancer	0	10	10	20	60	100

For cutpoint 4, the true positive rate is (20+60)/100 = .80 For cutpoint 4, the false positive rate is (8 + 2)/1000 = .01

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ISSN: 1471-2288

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