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Table 5 Summary of the validation with data set 1

From: Development and validation of MIX: comprehensive free software for meta-analysis of causal research data

 

MIX

STATA/CMA *

Items in odds ratio meta-analysis

Results

Results

Fixed effect (IV) odds ratio

  

OR – IV (95% CI)

0.7677 (0.7196 to 0.8190)

0.7677 (0.7196 to 0.8190)

Z (P value)

8.0073 (< 0.0001)

8.01 (< 0.0001)

Q (P value)

39.48 (0.17)

39.48 (0.17)

I2 (95% CI)

0.1895 (0 to 0.4749)

0.1895

Fail-safe N (tolerance level)

270 (175)

270 *

Rank correlation tau ** (P value)

0.1799 (0.141)

(0.141)

Egger's regression intercept (95% CI)

-0.2955 (-0.7880 to 0.1970)

-0.2955 (-0.7880 to 0.1970)

Macaskill's regression slope (P value)

0 (0.8396)

0 (0.840)

Trim-and-fill association measure (95% CI)

0.7744 (0.7260 to 0.8260)

0.774 (0.726 to 0.826)

Trim-and-fill imputed studies

6

6

Random effects (IV + t) odds ratio

  

OR – IV + t (95% CI)

0.7619 (0.6825 to 0.8506)

0.7619 (0.6825 to 0.8506)

Z (P value)

-4.84 (< 0.0001)

-4.84 (< 0.0001)

t2

0.117

0.117

Trim-and-fill association measure (95% CI)

0.7828 (0.6907 to 0.8871)

0.783 (0.691 to 0.887)

Trim-and-fill imputed studies

6

6

  1. This table shows the odds ratio validation of the inverse variance fixed effect and random effects analyses with data set 1. Though not shown here, the results from Mantel-Haenszel and Peto weighting were evaluated similarly and so were the other association measures (risk difference and risk ratio). The process was repeated for each data set. (*): Results marked with '*' were produced by CMA. (**): The rank correlation tau is a continuity corrected tau-b. Abbreviations: "IV" = inverse variance weighting, "OR" = odds ratio, "CI" = confidence interval, "IV+t" = inverse variance plus tau, which refers to random effects weighting according to the DerSimonian-Laird method.