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Table 2 Oral anticoagulation study characteristics

From: Assessing differential attrition in clinical trials: self-monitoring of oral anticoagulation and type II diabetes

Source

Inclusion Criteria

Duration of study mths.

Nos. assigned to Intervention & (%) drop out

Nos assigned to Control & (%) drop out

Intervention for self-monitoring group

Control group intervention

38 White 1989, US

Inpatients with a duration of OAT of at least 8 weeks §

2

26 (11.5)

24 (4.2)

Management by general internists

ACC

29 Horstkotte 1998, Germany

Outpatients with the St Jude Medical prosthesis ‡

N/A

75 (1.3)

75 (0)

INR twice a week and contact clinic by phone

PCP

34 Sawicki 1999, Germany

Any indication for anticoagulation and life long treatment ‡

6

90 (14.4)

90 (7.8)

3 educational sessions. SM

PCP

23 Beyth 2000, US

Inpatients §

6

163 (22.1)

162 (0)

1-hour education session and contact clinic by phone

PCP

24 Cromheecke 2000, Holland

Long term OAT at least 6 months treatment ‡

3

101 (0)

100 (0)

2-educational sessions, SM

ACC

32 Kortke 2001, Germany

Patients after mechanical heart valve surgery ‡

24

305 (8.9)

295 (21.4)

Trained in self-monitoring 6–11 days after operation

PCP

35 Sidhu 2001, UK

Patients after mechanical heart valve surgery ‡

24

51 (33.3)

49 (2.0)

2-educational sessions, SM

PCP

25 Fitzmaurice 2000, UK

Long term OAT at least 6 months treatment ‡

6

30 (23.3)

26 (0)

2-educational workshops, SM

PCP

27 Gadisseur 2003, Holland

Long term OAT at least 3 months treatment ‡

6

99 (19.2)

161 (0)

3 educational sessions. SM by telephone

ACC

28 Gardiner 2004, UK

Long term OAT At least 8 months ‡

6

44 (43.2)

40 (2.5)

2-educational sessions 1 week apart

ACC

31 Khan 2004, UK

At least 12 months OAT with AF. Age > 65 yrs ‡

6

44 (9.1)

41 (4.9)

2 hour education session, contact by phone

ACC

36 Sunderji 2004, Canada

OAT for at least 1 month ¤

8

70 (28.6)

70 (0)

2-educational sessions, SM

PCP

33 Menendez-Jandula 2005, Spain

OAT for at least 3 months therapy ‡

11.8

368 (21.5)

369 (2.4)

2-educational sessions, taught by nurse. SM

ACC

37 Voller 2005, Germany

long term OAT with non valvular AF ‡

5

101 (19.8)

101 (0)

Standard training course of 3 sessions

PCP

26 Fitzmaurice 2005, UK

Unselected patients in a general practice population

12

337 (41.5)

280 (13.2)

2-educational sessions, taught by nurse. SM

PCP or ACC

30 Katz Unpublished, US

Long term OAT attending anticoagulation clinic ‡

12

101(0)

100(0)

All patients were trained by nurse, video, and tested with a skills and knowledge checklist prior to randomization

ACC

  1. § Coumatrack Monitor ‡ Coagucheck System ¤ Pro time Microcoagulation system ACC: Anticoagulation Clinic Care PCP: Primary Care physician managed SM: self adjusted treatment