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Table 3 Baseline differences in standard deviations, stratified by SF-36 scales. Each comparison refers to one SF-36 scale at baseline: Mean score in AMOS cohort minus mean score in corresponding cohort, divided by standard deviation of score in AMOS cohort. A negative difference indicates that AMOS cohorts have worse health status than corresponding cohorts at baseline.

From: Assessing the order of magnitude of outcomes in single-arm cohorts through systematic comparison with corresponding cohorts: An example from the AMOS study

SF-36 scale Median Interquartile range Ranges: Number (percentage) of comparisons N (total)
    ≤ -0.8 -0.79 to -0.5 -0.49 to -0.2 -0.19 to 0.19 0.2 to 0.49 0.5 to 0.79 ≥ 0.8  
Physical Functioning 0.14 -0.20 to 0.72 0 (0) 0 (0) 16 (26) 19 (31) 9 (15) 7 (11) 11 (18) 62 (100)
Role Physical -0.05 -0.40 to 0.30 3 (5) 6 (10) 15 (25) 15 (25) 18 (31) 2 (3) 0 (0) 59 (100)
Role Emotional -0.14 -0.39 to 0.07 1 (2) 9 (15) 15 (25) 26 (44) 7 (12) 1 (2) 0 (0) 59 (100)
Social Functioning -0.24 -0.56 to 0.18 7 (11) 14 (21) 15 (23) 14 (21) 10 (15) 5 (8) 1 (2) 66 (100)
Mental Health -0.41 -0.59 to -0.19 7 (11) 17 (27) 22 (35) 13 (21) 2 (3) 1 (2) 0 (0) 62 (100)
Bodily Pain -0.05 -0.41 to 0.13 7 (11) 7 (11) 10 (16) 29 (45) 6 (9) 4 (6) 1 (2) 64 (100)
Vitality -0.41 -0.63 to -0.22 10 (17) 12 (20) 24 (40) 13 (22) 1 (2) 0 (0) 0 (0) 60 (100)
General Health -0.54 -0.84 to -0.10 19 (30) 14 (22) 14 (22) 9 (14) 5 (8) 2 (3) 0 (0) 63 (100)
Physical Component Summary 0.40 -0.12 to 0.84 0 (0) 3 (11) 2 (7) 5 (19) 6 (22) 4 (15) 7 (26) 27 (100)
Mental Component Summary -0.17 -0.55 to 0.06 2 (7) 8 (27) 4 (13) 13 (43) 3 (10) 0 (0) 0 (0) 30 (100)