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Table 5 Baseline differences in standard deviations, stratified by diagnosis. Each comparison refers to one SF-36 scale at baseline: Mean score in AMOS cohort minus mean score in corresponding cohort, divided by standard deviation of score in AMOS cohort. A negative difference indicates that AMOS cohorts have worse health status than corresponding cohorts at baseline.

From: Assessing the order of magnitude of outcomes in single-arm cohorts through systematic comparison with corresponding cohorts: An example from the AMOS study

Diagnosis Median Interquartile range Ranges: Number (percentage) of comparisons N (total)
    ≤ -0.8 -0.79 to -0.5 -0.49 to -0.2 -0.19 to 0.19 0.2 to 0.49 0.5 to 0.79 ≥ 0.8  
Asthma -0.02 -0.20 to +0.27 0 (0) 4 (5) 15 (20) 34 (44) 17 (22) 7 (9) 0 (0) 77 (100)
Depression -0.25 -0.51 to +0.03 10 (13) 9 (12) 28 (36) 19 (24) 9 (12) 0 (0) 3 (4) 78 (100)
Low back pain -0.05 -0.45 to +0.31 15 (7) 30 (15) 38 (19) 58 (29) 32 (16) 15 (7) 14 (7) 202 (100)
Migraine -0.42 -0.64 to -0.17 28 (19) 36 (24) 48 (32) 31 (21) 6 (4) 1 (1) 0 (0 150 (100)
Neck pain -0.37 -0.66 to -0.12 1 (10) 3 (30) 2 (20) 3 (30) 0 (0) 1 (10) 0 (0) 10 (100)
Total -0.22 -0.53 to +0.13 55 (11) 82 (16) 131 (25) 144 (28) 64 (12) 24 (5) 17 (3) 517 (100)