Skip to main content

Table 6 Outcome comparisons in effect sizes, stratified by diagnosis. Each comparison refers to one SF-36 scale at the last evaluable follow-up of the corresponding cohort: Mean difference from baseline in AMOS cohort minus mean difference from baseline in corresponding cohort, divided by standard deviation of baseline score of AMOS cohort. A positive difference indicates that AMOS cohorts show larger improvements than corresponding cohorts.

From: Assessing the order of magnitude of outcomes in single-arm cohorts through systematic comparison with corresponding cohorts: An example from the AMOS study

Diagnosis

Median

Interquartile range

Ranges: Number (percentage) of comparisons

N (total)

   

≤ -0.8

-0.79 to -0.5

-0.49 to -0.2

-0.19 to 0.19

0.2 to 0.49

0.5 to 0.79

≥ 0.8

 

Asthma

0.05

-0.18 to 0.30

1 (1)

4 (5)

13 (17)

33 (43)

18 (23)

6 (8)

2 (3)

77 (100)

Depression

0.17

-0.09 to 0.37

3 (4)

4 (5)

6 (8)

26 (33)

28 (36)

9 (12)

2 (3)

78 (100)

Low back pain

0.12

-0.12 to 0.33

9 (4)

10 (5)

22 (11)

77 (38)

57 (28)

21 (10)

6 (3)

202 (100)

Migraine

0.10

-0.08 to 0.35

0 (0)

2 (1)

16 (11)

77 (51)

34 (23)

14 (9)

7 (5)

150 (100)

Neck pain

0.44

0.23 to 0.54

0 (0)

0 (0)

1 (10)

1 (10)

5 (50)

3 (30)

0 (0)

10 (100)

Total

0.11

-0.11 to 0.35

13 (3)

20 (4)

58 (11)

214 (41)

142 (27)

53 (10)

17 (3)

517 (100)