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Table 6 Outcome comparisons in effect sizes, stratified by diagnosis. Each comparison refers to one SF-36 scale at the last evaluable follow-up of the corresponding cohort: Mean difference from baseline in AMOS cohort minus mean difference from baseline in corresponding cohort, divided by standard deviation of baseline score of AMOS cohort. A positive difference indicates that AMOS cohorts show larger improvements than corresponding cohorts.

From: Assessing the order of magnitude of outcomes in single-arm cohorts through systematic comparison with corresponding cohorts: An example from the AMOS study

Diagnosis Median Interquartile range Ranges: Number (percentage) of comparisons N (total)
    ≤ -0.8 -0.79 to -0.5 -0.49 to -0.2 -0.19 to 0.19 0.2 to 0.49 0.5 to 0.79 ≥ 0.8  
Asthma 0.05 -0.18 to 0.30 1 (1) 4 (5) 13 (17) 33 (43) 18 (23) 6 (8) 2 (3) 77 (100)
Depression 0.17 -0.09 to 0.37 3 (4) 4 (5) 6 (8) 26 (33) 28 (36) 9 (12) 2 (3) 78 (100)
Low back pain 0.12 -0.12 to 0.33 9 (4) 10 (5) 22 (11) 77 (38) 57 (28) 21 (10) 6 (3) 202 (100)
Migraine 0.10 -0.08 to 0.35 0 (0) 2 (1) 16 (11) 77 (51) 34 (23) 14 (9) 7 (5) 150 (100)
Neck pain 0.44 0.23 to 0.54 0 (0) 0 (0) 1 (10) 1 (10) 5 (50) 3 (30) 0 (0) 10 (100)
Total 0.11 -0.11 to 0.35 13 (3) 20 (4) 58 (11) 214 (41) 142 (27) 53 (10) 17 (3) 517 (100)