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Table 1 Description of our meta-ethnography

From: Conducting a meta-ethnography of qualitative literature: Lessons learnt

Experiences of tuberculosis treatment: A meta-ethnographic analysis of facilitators and barriers to inform the development of an adherence-promoting intervention

Aim

To determine barriers and facilitators of tuberculosis adherence

Search strategy

Text words included: Tuberculosis, adherence, compliance and concordance; obtained 7814 abstracts

Quality assessment

Assessed for quality using 13 criteria, extracted data

Synthesis approach

Meta-ethnographic analysis of 44 primary studies using both reciprocal translation and line of argument synthesis to develop a third order interpretation.

Key findings

A model that indicated adherence is related to: structural factors, social influence, organisation of treatment and care, and factors related to the disease

Hypotheses emerging from the synthesis

Increasing the visibility of TB programmes in the community may increase knowledge and improve attitudes towards TB

Providing more information about the disease and treatment to patients and communities

Increased support from family, peers and social networks

Minimizing costs and unpleasantness related to clinic visits and increasing flexibility and patient autonomy

Increasing flexibility in terms of patient choice of treatment plan and type of support

Increasing the patient centredness of interactions between providers and clients

Addressing 'structural' and 'personal' factors, for example through micro-financing and other empowerment initiatives

Providing more information about the effects of medication to reduce the risk of patients becoming non-adherent when experiencing treatment side effects