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Table 2 Standardized mean differences (SMD) for changes from baseline grouped by patient- and observer-reported outcome.

From: Spontaneous improvement in randomised clinical trials: meta-analysis of three-armed trials comparing no treatment, placebo and active intervention

 

No. of treatment arms

SMD (95% confidence interval)

I2 (%)

No treatment

   

Observer-reported

11

-0.28 (-0.56 to -0.01)

20

Patient-reported

26

-0.22 (-0.36 to -0.09)

30

Placebo

   

Observer-reported

11

-0.50 (-0.81 to -0.20)

40

Patient-reported

26

-0.42 (-0.62 to -0.22)

63

Active treatment

   

Observer-reported

16

-0.92 (-1.22 to -0.62)

56

Patient-reported

36

-1.04 (-1.22 to -0.87)

59