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Table 3 NNTs derived from consensus thresholds for MIC for the RMDQ (95% CI)

From: Estimating the number needed to treat from continuous outcomes in randomised controlled trials: methodological challenges and worked example using data from the UK Back Pain Exercise and Manipulation (BEAM) trial

 

Exercise

Manipulation

Combined

Three months

      

Improvement, 5 points

8.2

(4.9 to 25.0)

5.2

(3.7 to 8.8)

4.8

(3.5 to 7.8)

Improvement, 30%

9.0

(5.0 to 44.5)

5.4

(3.8 to 9.9)

4.4

(3.3 to 7.0)

Benefit, 5 points

6.6

(4.1 to 16.6)

5.1

(3.6 to 9.3)

4.3

(3.1 to 7.0)

Benefit, 30%

5.1

(3.4 to 10.7)

5.0

(3.4 to 9.8)

3.3

(2.5 to 4.9)

12 months

      

Improvement, 5 points

*

-

8.4

(5.0 to 28.6)

9.0

(5.2 to 37.8)

Improvement, 30%

*

-

8.0

(4.9 to 24.3)

7.1

(4.5 to 17.9)

Benefit, 5 points

*

-

7.8

(4.5 to 29.0)

7.2

(4.3 to 22.8)

Benefit, 30%

*

-

6.9

(4.1 to 21.1)

5.8

(3.7 to 13.2)

  1. * Analyses were not performed as no mean difference was reported between the exercise and best care groups at 12 months