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Table 1 Tabulation of an hypothetical diagnostic test accuracy meta-analysis. Columns T1,T2,T3 indicate results for the 3 possible index tests. Columns T4,T5 indicate results for the 2 possible reference tests. + indicates a positive test result, - a negative test result. NA indicates that the test was not performed in that particular study. The observed frequency column report the number of subjects with a specific test result pattern in each study

From: A general framework for comparative Bayesian meta-analysis of diagnostic studies

Study Index tests Reference Observed
Nr. T 1 T 2 T 3 T 4 T 5 Frequency
1 + + NA + NA 30
1 + + NA - NA 1
1 + - NA + NA 3
1 + - NA - NA 6
1 - + NA + NA 0
1 - + NA - NA 3
1 - - NA + NA 8
1 - - NA - NA 160
2 + + + NA + 49
2 - - - NA - 99
3 + NA NA + NA 115
3 - NA NA - NA 244
4 + NA NA NA + 11
4 - NA NA NA - 19
5 NA + NA + NA 66
5 NA - NA - NA 29
6 + NA + NA + 27
6 - NA - NA - 56
7 NA + + NA + 77
7 NA - - NA - 13
8 + + + NA NA 143
8 - - - NA NA 85