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Table 3 Subgroup identification and analysis of 52 squamous cell carcinoma patients using a leave-one-out cross validation for five classification methods. There were 26 patients in ACT and 26 patients in OBS

From: Subgroup identification for treatment selection in biomarker adaptive design

 

DLDA

ASD (−1,1)

ASD (−1,2)

ASD (−2,1)

ASD (−2,2)

Comparison 1

0.138

0.138

0.138

0.138

0.138

Comparison 2

0.07

0.125

0.149

0.428

0.114

Comparison 3

0.039

0.083

0.847

0.125

0.008

Comparison 4

1.25E-08

0.001

0.689

0.267

0.143

Comparison 5

0.697

0.697

0.938

0.791

0.034

g+ (T)a

6.79 (24)

6.71 (25)

6.71 (23)

6.71 (17)

5.21 (6)

g+ (C)

5.68 (23)

5.68 (23)

5.44 (22)

3.00 (15)

6.59 (8)

g− (T)

1.21 (2)

1.32 (1)

6.54 (3)

6.54 (9)

6.79 (20)

g− (C)

3.17 (3)

3.17 (3)

4.43 (4)

5.68 (11)

3.09 (18)

  1. Each method classified patients into 4 subgroups: g+ (T), g+ (C) g− (T) and g− (C)
  2. aMedian survival time (year) in the subgroup and the number of patients in the subgroup in parentheses