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Table 3 Summary of study design and population characteristics of the intervention in the evidence map

From: Creating a literature database of low-calorie sweeteners and health studies: evidence mapping

Intervention studies (n = 208)
Study design N (%) Population N (%)
 RCT-c 119 (57.7)  Adults 183 (88 %)
 RCT-p 58 (27.9)  Children 14 (7 %)
 nRCT-c 21 (10.1)  Adolescents 2 (1 %)
 nRCT-p 2 (1.0)  Mixed 6 (3 %)
 Single arm 6 (2.9)  Unsure 2 (1 %)
 Unclear 1 (0.5) Baseline health N (%)
Length N (%)  Healthy 140 (68 %)
 < 1 day 124 (60.1)  Overweight/Obese 19 (9 %)
 2 day-1 month 37 (17.8)  Diabetic 17 (8 %)
 1–6 months 30 (14.4)  Mixed 14 (7 %)
 6 months–1 year 1 (0.5)  Other 17 (8 %)
 > 1 year 7 (3.3) Age, Mean (Range) 31 (8–73)
 Not reported 8 (3.8) BMI, Mean (Range) 25.6 (16.1–42.3)
Sample size, Mean (range) 48 (2–732) % Male 51 % (0–100 %)
  1. Data missing for age: n = 2, % male, n = 29, and BMI n = 87. RCT-c Randomized controlled trial-crossover design, RCT-p Randomized controlled trial-parallel design, nRCT-c Non-randomized controlled trial-crossover design, nRCT-p Non-randomized controlled trial-parallel design. Mixed or other: A mixture of healthy and overweight, healthy and diabetic, or overweight and diabetic population, and other population: patient or people with disease at baseline