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Table 1 Characteristics of the hospital-based pediatric studies sponsored by the Assistance Publique-Hôpitaux de Paris between 2002 and 2008

From: Academic pediatric clinical research: factors associated with study implementation duration

Characteristics Observational studies (n = 72) Interventional studies without drug therapy (n = 32) Interventional studies involving drug therapy (n = 35) p-value Excluded studies (n = 6)
       NA
Funding mechanism     0.07   5
Government 39 (54) 20 (63) 12 (34)   1 (100)
External 20 (28) 4 (13) 14 (40)   0 (0)
Internal 13 (18) 8 (25) 9 (26)   0 (0)
Year of grant     -   0
2002 17 (24) 1 (3) 3 (9)   1 (17)
2003 5 (7) 2 (6) 3 (9)   4 (67)
2004 9 (13) 2 (6) 5 (14)   1 (17)
2005 15 (21) 1 (3) 7 (20)   0
2006 6 (8) 5 (16) 6 (17)   0
2007 12 (17) 12 (38) 9 (26)   0
2008 8 (11) 9 (28) 2 (6)   0
Coordinator center     0.31   0
Pediatric hospital 28 (39) 15 (47) 19 (54)   6 (100)
General hospital 44 (61) 17 (53) 16 (46)   0 (0)
Number of centers 6 [2;16] 5 [2;16] 3 [1;15] 0.78 1 [1;1] 1
Monocentric study 12 (17) 5 (15.6) 14 (40) 0.01 4 (80) 1
International study 1 (1) 0 (0) 4 (11) 0.006 0 (0) 0
Rare disease 50 (69) 20 (63) 27 (77) 0.43 4 (67) 0
Chronic disease 60 (83) 22 (69) 26 (74) 0.22 4 (67) 0
Study population     0.003   0
Pediatric 30 (42) 19 (59) 27 (77)   6 (100)
Mixed (children and adults) 42 (58) 13 (41) 8 (23)   0 (0)
Number of patients to include 150 [82;388] 128 [66;240] 60 [36;100] 0.12 20 [20;25] 3
Length of participation, months 0.2 [0.03;12] 4 [0.2;17] 8 [0.5;24] 0.61 0.1 [0.03;2] 2
Referenced in ClinicalTrials.gov 21 (29) 32 (100) 24 (69) <0.001 1 (17) 0
  1. Values shown are median [25th percentile; 75th percentile] and number (percentage)