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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers

Fig. 1

Distribution of the differences to be detected for controlled pain between the new treatment and its comparator selected by respondents in vignette 1 when: a the pain was controlled in 50 % of patients with reference treatment (high baseline risk) (n = 184), b the pain was controlled in 90 % of patients with reference treatment (low baseline risk) (n = 186). The difference between the percentage selected by a respondent and the baseline risk is the difference to be detected

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