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Table 1 Response options proposed to participants in the two clinical vignettes depending on baseline risk used

From: How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers

  Proportion of pain control in the experimental group when baseline risk was:
Vignette 1 Low (90 %) High (50 %)
Trial of a new analgesic to control pain in mild trauma injuries. 90.5
91.0
92.0
95.0
97.0
100.0
Open field
51.0
55.0
60.0
70.0
80.0
90.0
Open field
  Proportion of mortality/cancer recurrence in the experimental group when baseline risk was:
Vignette 2 Low (10 %) High (60 %)
Trial of a new adjuvant chemotherapy following primary surgery for an unnamed cancer in adults. 9.9
9.5
9.0
8.0
5.0
0.0
Open field
59.9
59.5
58.0
55.0
50.0
40.0
30.0
Open field