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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: Cohort Multiple Randomised Controlled Trials (cmRCT) design: efficient but biased? A simulation study to evaluate the feasibility of the Cluster cmRCT design

Fig. 1

Percentage bias and power of the four analysis methods for varying levels of patient refusal and correlation between individual patient refusal probabilities and risk. Clinician refusal = 0, correlation is negative, recruitment method 1 is used and ICC =0.025. The black line in the power graph represents the expected power in the trial. A lognormal frailty model is fitted to the data

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BMC Medical Research Methodology

ISSN: 1471-2288

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