Table 6 Estimations of fixed effect parameters (β _p ) _p=1,2,3 of the (cumulative,logistic, Z ₁,U ₂ ) model

Global Health Status

β ₂

0.098

0.070

0.166

β ₃

0.130

0.085

0.128

Physical functioning

β ₂

-0.150

0.077

0.051

β ₃

0.122

0.098

0.212

Role functioning

β ₂

-0.011

0.081

0.892

β ₃

0.157

0.103

0.131

Emotional functioning

β ₂

0.335

0.070

<.001^∗∗∗

β ₃

0.001

0.086

0.992

Cognitive functioning

β ₂

-0.002

0.054

0.972

β ₃

0.088

0.067

0.189

Social functioning

β ₂

0.010

0.073

0.888

β ₃

0.116

0.093

0.211

Fatigue

β ₂

-0.087

0.085

0.308

β ₃

-0.033

0.107

0.761

Nausea and vomiting

β ₂

-0.052

0.060

0.393

β ₃

-0.069

0.072

0.336

Pain

β ₂

-0.330

0.076

<.001^∗∗∗

β ₃

-0.188

0.092

0.040 ^∗

Dyspnea

β ₂

-0.060

0.075

0.420

β ₃

-0.093

0.088

0.295

Insomnia

β ₂

-0.359

0.080

<.001^∗∗∗

β ₃

0.046

0.083

0.627

Appetite loss

β ₂

-0.354

0.072

<.001^∗∗∗

β ₃

-0.026

0.080

0.747

Constipation

β ₂

-0.325

0.077

<.001^∗∗∗

β ₃

0.003

0.083

0.974

Diarrhea

β ₁

0.739

0.272

0.007 ^∗∗

β ₂

0.018

0.067

0.792

β ₃

-0.026

0.076

0.786

Financial difficulties

β ₂

-0.522

0.282

0.066

β ₃

0.302

0.208

0.146