
Setting

Results of simulations


Methods (Effect measures)

β
_{X}

Mean of estimates (Ratio scale)

Bias (Log scale)

Empirical standard error

Mean squared error

Mean standard error

Coverage (%)


SCCS (IRR)

log(1.0)

0.99

0.0125

0.1354

0.0185

0.1335

95.1

CCO (OR)
 
1.00

0.0005

0.2084

0.0434

0.2116

96.1

SSA (ASR)
 
0.99

0.0005

0.2373

0.0563

0.2454

96.3

SCCS (IRR)

log(3.0)

2.99

0.0030

0.0791

0.0063

0.0777

94.7

CCO (OR)
 
3.04

0.0121

0.18

0.0309

0.1732

94.8

SSA (ASR)
 
3.04

0.0119

0.2016

0.0408

0.2003

95.2

SCCS (IRR)

log(10.0)

9.98

0.0019

0.0438

0.0019

0.0446

95.5

CCO (OR)
 
10.30

0.0295

0.1663

0.0285

0.1604

94.4

SSA (ASR)
 
9.97

0.0026

0.1834

0.0336

0.1817

94.7

 Abbreviations ASR adjusted sequence ratio, CCO casecrossover, IRR incident rate ratio, OR odds ratio, SCCS selfcontrolled case series, SSA sequence symmetry analysis