Training cohort | Validation cohort | |||
---|---|---|---|---|
Controls | HCC cases | Controls | HCC cases | |
N | 5611 | 451 | 5611 | 451 |
Age at baseline (years) | 52.87 (7.28) | 54.67 (7.78) | 52.93 (7.39) | 54.89 (7.49) |
Male | 5498 (97.99%) | 449 (99.56%) | 5501 (98.04%) | 447 (99.11%) |
Female | 113 (2.01%) | 2 (0.44%) | 110 (1.96%) | 4 (0.89%) |
Race | ||||
White | 1954 (34.82%) | 173 (38.36%) | 2034 (36.25%) | 171 (37.92%) |
Black | 623 (11.10%) | 54 (11.97%) | 576 (10.27%) | 60 (13.30%) |
Other/Unknown | 3034 (54.07%) | 224 (49.67%) | 3001 (53.48%) | 220 (48.78%) |
Number of AFP tests | ||||
1 | 1598 (28.48%) | 116 (25.72%) | 1598 (28.48%) | 138 (30.60%) |
2 | 1297 (23.12%) | 119 (26.39%) | 1240 (22.10%) | 106 (23.50%) |
3-4 | 1480 (26.38%) | 119 (26.39%) | 1524 (27.16%) | 120 (26.61%) |
> 4 | 1236 (22.03%) | 97 (21.51%) | 1249 (22.26%) | 87 (19.29%) |
Months between AFP tests | 11.67 (11.00) | 10.30 (10.10) | 11.83 (11.26) | 10.93 (10.89) |
Baseline AFP in log2(ng/ml) | 2.92 (1.55) | 4.72 (2.78) | 2.95 (1.57) | 4.57 (2.95) |
Baseline ALT in log2(ng/ml) | 6.14 (1.03) | 6.31 (0.91) | 6.16 (1.05) | 6.35 (0.88) |
Baseline PLT in 1000’s | 147.97 (78.88) | 123.50 (66.06) | 148.51 (78.83) | 127.97 (76.08) |