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Table 3 Estimated prevalence of neurodevelopmental impairment after corrections for loss to follow-up using inverse probability weighting (IPW) and multiple imputation (MI)

From: Strategies for assessing the impact of loss to follow-up on estimates of neurodevelopmental impairment in a very preterm cohort at 2 years of age

 

Portugal

UK

Total

Crude

16.5 [13.1;20.5]

20.0 [16.6;24.0]

18.4 [15.9;21.2]

IPW complete cases

17.5 [14.4;21.1]

20.5 [17.9;23.3]

19.4 [17.4;21.6]

 % Change in prevalencea

6.1%

2.5%

5.4%

IPW imputed cases

18.3 [14.1;22.6]

20.8 [16.7;25.0]

20.0 [16.9;23.1]

 % Change in prevalence

10.9%

4.0%

8.7%

MI (total population)

17.4 [13.4;21.4]

21.9 [17.9;26.0]

20.4 [17.3;23.4]

 % Change in prevalence

5.5%

9.5%

10.9%

MI (Responders)

17.1 [13.3;20.8]

19.7 [16.1;23.4]

18.6 [16.0;21.2]

 % Change in prevalence

3.6%

−1.5%

1.1%

MI (Non-responders)

18.1 [8.9;27.2]

23.9 [17.2;30.6]

23.0 [17.4;28.7]

  1. MI models were adjusted for gestational age, multiple pregnancy, foreign-born mother or foreign ethnicity, mother's age, parity, breastfeeding at discharge, previous cesarean section, PPROM, antepartum hemorrhage, sex, Apgar at 5 min less than 7, any respiratory support, surfactant, bronchopulmonary dysplasia, any severe morbidity, congenital anomaly, surgery in neonatal unit, hospitalized in a level III unit, SES status, region and follow-up
  2. IPW model were adjusted for multiple pregnancy, foreign-born mother or foreign ethnicity, mother's age, parity, breastfeeding at discharge, previous cesarean section, PPROM, respiratory support MV and CPAP, surfactant, hospitalized in a level III unit, SES status and region
  3. apercent increase in estimated prevalence corrected for selection bias compared to the crude estimate