Fig. 1
From: Methods for the inclusion of real-world evidence in network meta-analysis
Network diagram including A randomised controlled trials (RCT) and B real-world evidence (RWE) studies for the treatment of relapsing remitting multiple sclerosis. Nodes (circles) in the diagram represent treatments included in the network meta-analysis, with node sizes being proportional to the number of subjects in each treatment arm. Edges (lines between nodes) represent the direct comparisons available between treatments with thickness of edges being proportional to the number of direct comparisons available. Numbers along edges represent the number of studies directly comparing treatments