Parameter | Set-up in our study | Explanation |
---|---|---|
Drug of interest | Hydroxychloroquine | drug for which we want to know all co-prescriptions after exposure |
Study period | 01/01/2008 to 12/31/2018 | study start and stop |
Time period | month | time interval between start and stop |
Time window | 24 months | potential exposure period before the event |
Covariates | age, sex, and severity | covariate to fit the model |
nknots | 1 | number of interior knots for the cubic spline to estimate the risk function |
Bootstraps | 1,000 | repeat on sample of the WCE model application |
Number of ATC classes | 1,081 | ATC classes level 5 |
Number of medical diagnoses | 4,200 | code CIM10 |
Number of procedures | 3,075 | we used “classification commune des actes médicaux”, a classification from the French National Insurance |