Skip to main content

Advertisement

Table 2 Power for detecting heterogeneity of treatment effect by varying degrees of balance among the components of the composite for a moderate heterogeneity pattern OR1, OR2= (0.65, 1.00) and ratio (p1:p2) of occurrence of components 1 and 2.

From: Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

Balance (p1:p2) Weighted DD Weighted RS Independent Random Effects GEE
1:1 85.3 85.8 88.1 88.2 90.0
1:3 77.0 77.1 75.4 75.4 78.7
1:5 65.0 65.0 59.4 59.4 62.8
3:1 79.1 79.1 79.5 79.9 82.3
5:1 70.3 70.3 68.2 68.6 71.1