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Featured article: Assessing risk of bias: a proposal for a unified framework for observational studies and randomized trials
Luijendijk et al propose a unified framework that enables the coherent assessment of bias across designs and three sources of bias were illustrated with graphs that visually represent researchers’ assumptions about the relationships between the investigated variables (causal diagrams).
This study by Bisset et al aimed to investigate the influence of Twitter in promoting surgical recruitment in The Emergency Laparotomy and Frailty (ELF) Study. The discuss that the ELF Study over-recruited by nearly 100%, reaching over 200,000 people across the U.K, and that branding enhanced tweet aesthetics and helped increase tweet engagement, stimulating discussion and healthy competition amongst clinicians to aid trial recruitment.
Featured article: Joint analysis of duration of ventilation, length of intensive care, and mortality of COVID-19 patients: a multistate approach
Hazard et al used multistate models to study COVID-19 patients’ time-dependent progress and provide a statistical framework to estimate hazard rates and transition probabilities. Their approach gives important insights into the progress of COVID-19 patients in terms of ventilation duration, length of ICU stay, and mortality.
Aims and scope
Call for Papers: Methodologies for COVID-19 research and data analysis
BMC Medical Research Methodology announces this upcoming collection focusing on methodological approaches to medical research and data analysis related to COVID-19. Find more information and explore recent publications here.Read More
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The 2020 Nobel Prize for Physiology or Medicine was awarded to Harvey J. Alter, Michael Houghton and Charles M. Rice for their discovery of Hepatitis C virus. In celebration of what they started and showcasing areas of research that have since emerged, we here present a collection of articles from the BMC Biology, BMC Medicine, Genome Medicine and the BMC Series Journals on biology, diagnosis and treatment and wider public health and medical outcomes of the Hepatitis C virus and its infection.
BMC Series Focus Issue
With World Animal Day falling on October 4th, the BMC series has decided to dedicate this month’s focus issue to animal models. Browse our titles for insight into recent research in the field, including growth regulation, lifespan variation, nephrotoxicity, cancer, lipid metabolism, autism, temperature-dependent development, drug resistance, inflammatory responses, disease resistance, sperm dynamics and antimicrobial residues in fish.