Figure 3From: Designing cost-efficient randomized trials by using flexible recruitment strategies Plots of optimum total costs (A) and sample sizes (B) as a function of screening severity threshold a . The solid vertical lines indicate the optimum screening severity threshold for minimum total cost under the two stage procedure. The dashed vertical line indicates the optimum screening severity threshold for minimum total cost under the single stage procedure. In B, the gray solid line is the screening sample size under the single stage procedure.Back to article page