|
OHTS
|
|---|
|
Variables
|
Parameters for IOP change and the effects of covariates on class membership
|
Effects on POAG
|
|---|
| |
Class 1
|
Class2 (Ref.)
|
Class 3
|
Class 4
|
Class 5
|
Class 6
| |
|---|
|
Class Size IOP Change
|
14.2%
|
27.1%
|
21.1%
|
9.1%
|
17.6%
|
10.9%
| |
|---|
|
I
|
17.58(0.20)#
|
19.83(0.21)#
|
22.30(0.21)#
|
22.82(0.79)#
|
24.74(0.22)#
|
27.70(0.28)#
|
-
|
|
L
|
−0.57(0.08)#
|
−0.53(0.06)#
|
−0.47(0.09)#
|
−0.95(0.30)#
|
−0.20(0.09)*
|
0.16(0.17)
|
-
|
|
Q
|
0.06(0.01)#
|
0.05(0.01)#
|
0.05(0.01)#
|
0.07(0.04)
|
0.02(0.02)
|
−0.05(0.03)
|
-
|
|
V
|
4.36(0.27)#
|
4.30(0.32)#
|
4.80(0.25)#
|
16.07(1.46)#
|
4.66(0.31)#
|
12.15(1.15)#
|
-
|
|
Covariates
| | | | | | | |
|
Intercept
|
−2.64(0.63)#
| |
2.08(0.47)#
|
−0.06(0.47)
|
2.35(0.54)#
|
1.04(0.61)
|
-
|
|
TRT
|
1.60(0.66)*
|
-
|
−3.25(0.35)#
|
−2.19(0.63)#
|
−5.98(0.56)#
|
−6.46(0.70)#
|
0.16(0.29)
|
|
MALE
|
0.25(0.23)
|
-
|
−0.99(0.24)#
|
0.24(0.27)
|
−0.68(0.28)*
|
−0.22(0.30)
|
0.23(0.19)
|
|
RACEB
|
−0.10(0.27)
|
-
|
−0.37(0.30)
|
0.75(0.31)*
|
−0.91(0.34)*
|
0.05(0.37)
|
−0.05(0.24)
|
|
AGE
|
0.06(0.12)
|
-
|
−0.01(0.12)
|
0.08(0.16)
|
−0.05(0.14)
|
0.13(0.15)
|
0.18(0.09) *
|
|
IOP0
|
−0.79(0.18)#
|
-
|
0.21(0.22)
|
1.03(0.36)*
|
0.89(0.18)#
|
1.73(0.22)#
|
−0.10(0.11)
|
|
CCT
|
−0.35(0.12)*
|
-
|
0.18(0.11)
|
−0.08(0.17)
|
0.14(0.13)
|
0.09(0.16)
|
−0.64(0.13)#
|
|
PSD
|
0.13(0.11)
|
-
|
0.04(0.11)
|
0.08(0.13)
|
0.17(0.13)
|
0.12(0.15)
|
0.23(0.10)*
|
|
VCD
|
0.06(0.11)
|
-
|
−0.08(0.12)
|
−0.15(0.17)
|
−0.10(0.13)
|
−0.09(0.15)
|
0.60(0.10)#
|
|
BB
|
−0.60(0.48)
|
-
|
−0.37(0.61)
|
- **
|
−0.30(0.62)
|
−1.21(0.77)
|
0.19(0.57)
|
|
CHB
|
−0.19(0.37)
|
-
|
−0.32(0.42)
|
0.47(0.45)
|
−0.42(0.44)
|
−0.50(0.49)
|
0.09(0.31)
|
|
DM
|
−0.23(0.35)
|
-
|
0.22(0.32)
|
−0.71(0.45)
|
0.23(0.36)
|
0.64(0.40)
|
−1.67(0.53)*
|
|
HEART
|
0.70(0.44)
|
-
|
0.10(0.49)
|
0.43(0.56)
|
−0.09(0.56)
|
−0.48(0.73)
|
0.71(0.29)*
|
|
HBP
|
0.47(0.24)*
|
-
|
0.40(0.27)
|
0.06(0.34)
|
0.41(0.30)
|
0.66(0.33)*
|
0.08(0.22)
|
|
EGPS
|
|
Variables
|
Parameters for IOP change and the effects of covariates on class membership
|
Effects on POAG
| |
| |
Class1 (Ref.)
|
Class 2
|
Class 3
|
Class 4
|
Class 5
| | |
|
Class Size IOP Change
|
26.3%
|
20.1%
|
29.3%
|
12.9%
|
11.4%
| | |
|
I
|
18.66(0.25) #
|
18.24(0.18)#
|
21.24(0.20)#
|
21.85(0.47)#
|
24.33(0.34)#
|
-
| |
|
L
|
−0.34(0.14)*
|
−1.29(0.18)#
|
−0.25(0.11)*
|
−1.76(0.28)#
|
0.06(0.26)
|
-
| |
|
Q
|
0.05(0.03)
|
0.11(0.04)*
|
0.02(0.03)
|
0.02(0.07)
|
−0.08(0.07)
|
-
| |
|
V
|
3.79(0.23)#
|
3.75(0.25)#
|
4.59(0.24)#
|
7.12(0.85)#
|
12.17(1.32)#
|
-
| |
|
Covariates
| | | | | | | |
|
Intercept
|
-
|
−0.84(0.33)*
|
0.30(0.28)
|
−0.85(0.58)
|
−0.71(0.34)*
|
-
| |
|
TRT
|
-
|
0.36(0.27)
|
−0.65(0.23)*
|
−0.58(0.37)
|
−1.79(0.37)#
|
−0.01(0.21)
| |
|
MALE
|
-
|
−0.35(0.29)
|
0.14(0.23)
|
0.18(0.40)
|
0.38(0.33)
|
−0.24(0.22)
| |
|
Black
|
-
|
-
|
-
|
-
|
-
|
-
| |
|
AGE
|
-
|
−0.09(0.16)
|
0.01(0.13)
|
0.40(0.23)
|
0.45(0.20)*
|
0.16(0.10)
| |
|
IOP0
|
-
|
−0.61(0.24)*
|
0.82(0.17)#
|
1.24(0.24)#
|
1.79(0.23)#
|
0.11(0.13)
| |
|
CCT
|
-
|
−0.33(0.13)*
|
−0.14(0.12)
|
−0.43(0.15)*
|
0.09(0.15)
|
−0.36(0.12)*
| |
|
PSD
|
-
|
0.27(0.16)
|
−0.23(0.14)
|
−0.18(0.24)
|
−0.41(0.23)
|
0.18(0.09)*
| |
|
VCD
|
-
|
−0.13(0.17)
|
−0.03(0.13)
|
0.72(0.26)*
|
0.17(0.16)
|
0.46(0.12)#
| |
|
BB
|
-
|
−0.17(0.50)
|
−0.82(0.52)
|
- **
|
−0.58(0.69)
|
−0.07(0.41)
| |
|
CHB
|
-
|
−0.10(0.56)
|
−0.97(0.52)
|
0.89(1.03)
|
−1.22(0.79)
|
−0.28(0.47)
| |
|
DM
|
-
|
−0.46(0.52)
|
0.12(0.45)
|
−1.32(1.27)
|
0.82(0.81)
|
−0.18(0.54)
| |
|
HEART
|
-
|
0.78(0.41)
|
0.11(0.44)
|
−0.83(0.77)
|
−0.79(0.61)
|
0.74(0.32)*
| |
|
HBP
|
-
|
0.02(0.36)
|
0.53(0.30)
|
−1.27(0.90)
|
0.11(0.54)
|
0.24(0.26)
| |
- *: p < 0.05; #: p < 0.001; **: Not estimable due to zero count of beta blocker use in the given class.
