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Table 3 Simulation results demonstrating the application of the DeLong et al. method [[3]] and the U-statistics based method [[9]] for comparing two fixed models under the null hypothesis

From: On the assessment of the added value of new predictive biomarkers

  

N 0=50N 1=50

N 0=50N 1=100

N 0=100N 1=200

ρ=0

μ=0

0.0531/0.0547

0.0501/0.0507

0.0515/0.0521

 

μ=1

0.0515/0.0527

0.0542/0.0558

0.0503/0.0511

 

μ=1.5

0.0482/0.0498

0.0503/0.0512

0.0496/0.0500

ρ=0.6

μ=0

0.0507/0.0530

0.0488/0.0505

0.0515/0.0526

 

μ=1

0.0457/0.0493

0.0501/0.0519

0.0485/0.0500

 

μ=1.5

0.0453/0.0486

0.0444/0.0471

0.0501/0.0517

  1. Fraction of significant findings in 20,000 Monte Carlo trials at statistical significance cut-off of 0.05 for the DeLong et al. method and the U-statistics based method respectively.
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BMC Medical Research Methodology

ISSN: 1471-2288

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