Coefficient for true effect of confounder (β
4)
|
Correlation between true value of confounder and exposure
|
2 (sd of estimate)
|
---|
| |
σ
v
2 = 0
|
σ
v
2 = 1
|
σ
v
2 = 2
|
σ
v
2 = 4
|
σ
v
2 = 9
|
---|
1.0
|
0.2
|
1.001 (0.073)
|
1.103 (0.076)
|
1.136 (0.077)
|
1.162 (0.078)
|
1.182 (0.079)
|
|
0.5
|
1.001 (0.081)
|
1.287 (0.079)
|
1.365 (0.079)
|
1.422 (0.078)
|
1.463 (0.078)
|
|
-0.5
|
1.000 (0.080)
|
0.715 (0.079)
|
0.637 (0.079)
|
0.580 (0.078)
|
0.539 (0.078)
|
-1.0
|
0.2
|
1.001 (0.073)
|
0.898 (0.077)
|
0.865 (0.078)
|
0.839 (0.078)
|
0.819 (0.079)
|
|
0.5
|
1.001 (0.081)
|
0.715 (0.079)
|
0.637 (0.079)
|
0.579 (0.078)
|
0.539 (0.078)
|
|
-0.5
|
1.000 (0.080)
|
1.286 (0.080)
|
1.364 (0.079)
|
1.421 (0.079)
|
1.462 (0.078)
|
- True values of coefficients β
1 = 1 (binary genotype), β
2 = 1 (continuous exposure), β
3 = 1 (interaction term), β
4 (confounder) given in first column. Simulations based on 10,000 simulations of 1000 observations. Monte Carlo error is 1% of the empirical standard deviation of the estimates for
2; approximately 0.0008.