Characteristic | Baseline characteristics | Consolidation treatment | |||
---|---|---|---|---|---|
414 | None received 118 (28.50 %) | Received 296 (71.50 %) | P | ||
Age (years) | Mean (SD) | Mean (SD) | Mean (SD) | ||
56.00 (7.21) | 57.08 (6.48) | 55.57 (7.44) | 0.07 | ||
Median (IQR) | Median (IQR) | Median (IQR) | |||
57.47 (51.57–61.74) | 58.23 (52.40–62.28) | 56.76 (51.08–61.49) | |||
Sex | Male | 236 (57.00 %) | 62 (52.54 %) | 174 (58.78 %) | 0.25 |
Female | 178 (43.00 %) | 56 (47.46 %) | 122 (41.22 %) | ||
Haemoglobin (g/dL) | >10.5 normal | 251 (60.63 %) | 67 (56.78 %) | 184 (62.16 %) | 0.31 |
≤10.5 abnormal | 163 (39.37 %) | 51 (43.22 %) | 112 (37.84 %) | ||
Platelets (×109 per L) | >150 normal | 369 (89.13 %) | 107 (90.68 %) | 262 (88.51 %) | 0.52 |
≤150 abnormal | 45 (10.87 %) | 11 (9.32 %) | 34 (11.49 %) | ||
Creatinine (μmol/dL) | ≤1.2 normal | 326 (78.74 %) | 94 (79.66 %) | 232 (78.38 %) | 0.77 |
>1.2 abnormal | 88 (21.26 %) | 24 (20.34 %) | 64 (21.62 %) | ||
LDH (U/L) | ≤190 normal | 59 (14.25 %) | 24 (20.34 %) | 35 (11.82 %) | 0.03 |
>190 abnormal | 355 (85.75 %) | 94 (79.66 %) | 261 (88.18 %) | ||
ISS stage | 1 | 180 (43.48 %) | 44 (37.29 %) | 136 (45.95 %) | 0.26 |
2 | 162 (39.13 %) | 50 (42.37 %) | 112 (37.84 %) | ||
3 | 72 (17.39 %) | 24 (20.34 %) | 48 (16.22 %) | ||
IgA isotype | IgA | 81 (19.57 %) | 25 (21.19 %) | 56 (18.92 %) | 0.60 |
Not IgA | 333 (80.43 %) | 93 (78.81 %) | 240 (81.08 %) | ||
Del(13q) | absent | 214 (51.69 %) | 61 (51.69 %) | 153 (51.69 %) | 0.99 |
present | 200 (48.31 %) | 57 (48.31 %) | 143 (48.31 %) | ||
Del(17p) | absent | 385 (93.00 %) | 110 (93.22 %) | 275 (92.91 %) | 0.91 |
present | 29 (7.00 %) | 8 (6.78 %) | 21 (7.09 %) | ||
T(4;14) | absent | 331 (79.95 %) | 98 (83.05 %) | 233 (78.72 %) | 0.32 |
present | 83 (20.05 %) | 20 (16.95 %) | 63 (21.28 %) | ||
Treatment arm | A experimental | 200 (48.31 %) | 53 (44.92 %) | 147 (49.66 %) | 0.38 |
B control | 214 (51.69 %) | 65 (55.08 %) | 149 (50.34 %) |